MC-FANを用いた血液流動性 (血液通過時間) 測定の再現性

概要

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Blood rheological property (blood passage time) is an index of cardiovascular disease risks. There are several ways to measure blood reological property, but because of the complex properties of blood, each has some limitations. MC-FAN is known to be a useful filter method for monitoring the flow of blood. However, the accuracy of this method has not been thoroughly tested. The purpose of this study was to verify the test-retest repeatability of blood passage time using MC-FAN. (Methods) The blood rheological property was, in this study, defined as the passage time of a whole blood sample measured by MC-FAN. The subjects were 14 male (age; 36.1±15.3yr) and 10 female (43.1±20.4yr) volunteers. After two-consecutive measurements the test-retest correlation, and coefficient of variation (CV) were calculated. (Results) The correlation coefficient was 0.968 (P<0.05), and %CV was only 0.52%. (Conclusion) The average of the blood passage time was 50s in the healthy men and 40 s in the healthy women. Repeatability of blood rheological property (blood passage time) was high, and MC-FAN had an error of only 0.25s on the blood passage time.
日本バイオレオロジ-学会の論文