好酸球性胃炎の1例

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Until now, many cases with lesions of eoshinophilic infiltration of the stomach have been reported. These lesions are classified into three different types by Tanaka (1975), that is (1) localized polypoid, (2) diffuse thickened and (3) parasitic granulomatous. They are thought to have individually different pathogenesis. The diffuse thickened type consists with eoshinophilic gastritis, proposed by Doniach and McKeown (1951), and this type is said to have a relationship with allergic lesions and is considered as an uncommon lesion. Only about 10 similar case reports have been found in the literature in our country. We have encountered a case with diffuse massive eoshinophilic infiltration of the gastric wall. And the lesion is similar with the diffuse thickened type and eoshinophilic gastritis. The patient, aged 48, housewife, was diagnosed as gastric cancer because of the deformity of the stomach by the barium-meal radiography. Total gastrectomy was performed. The totally resected stomach revealed thickening of the wall, especially of musular layer. The lesion extends from the fundus to the antrum of the stomach. Microscopic study of many sections of the resected stomach showed thickening of the wall due to marked diffuse eoshinophilic infiltration in the submucosa, muscularis, and subserosa, specially muscularis. Slight eoshinophilic infiltration was revealed in the spleen and the surgically biopsied liver. Ten per cent of eoshinophilic leukocytosis in the peripheral blood was disclosed 2 months after the gastrectomy. There is no evidence of parasitic infection and no history of allergy in this case. We could not find any allergenic factor in this case.
学校法人昭和大学・昭和医学会の論文

好酸球性胃炎の1例

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