発作性夜間血色素尿症の1例

概要

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A 27-year-old male, with chief complaints of lumbago and hemoglobinuria, was admitted to our hospital on Feb. 28th, 1966. His peripheral blood showed no abnomalities except a slight leucopenia. Appearent half survival time of erythrocytes, determined by Cr51-method, shortened to 10.5 days. The osmotic resistence of erythrocytes, before and after incubation at 37°C for 24 hours, was within normal range. Ham's, Crosby's, and Hegglin's tests were all positive. On the other hand, Wassermann's Donath-Landsteiner's, Coomb's (direct and indirect) and Rosenbach's tests were all negative. From these clinical and laboratory examination, he was diagnosed as a typical case of paroxysmal nocturnal heamoglobinuria.
学校法人昭和大学・昭和医学会の論文