EDTA-Dependent Pseudothrombocytopenia Associated with Epstein-Barr Virus Infection

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Pseudothrombocytopenia was identified as a phenomenon when it became possible to count platelets using an automatic blood cell counter. This phenomenon occurs when platelets become coagulated with ethylene diamine tetratic acetic acid; EDTA.A 28-year-old-man presented with a history of sore throat and neck pain. Based on blood test findings, infectious mononucleosis was diagnosed. After he was hospitalized, the platelet count was decreased (5.2×104/μl). So we changed the anticoagulant from EDTA to heparin sodium. Since we suspected pseudothrombocytopenia (PTCP), we measured the platelet count again and found that the platelet count was elevated (21.0×104/μl). PTCP should be considered when Epstein-Barr virus infection is diagnosed. This is a rare case of pseudothrombocytopenia accompanied by Epstein-Barr virus infection.
耳鼻咽喉科臨床学会の論文