頭頚部悪性腫瘍に対する凍結術併用療法

概要

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Thirty-one patients with malignant neoplasm of the head and neck were treated with combined cryosurgery in hopes of a primary cure. Clinical effects of cryosurgery in combination with radiation, intra-arterial infusion and/or surgery were evaluated retrospectively, and merits, demerits and indication of cryosurgery were discussed. Twenty of the thirty-one cases (64.5%) developed no recurrence in one year or more.There were basically two different purposes in applying cryosurgery. In one group of patients, cryosurgery was applied in combination with radiation and chemotherapy in order to avoid radical surgery (Group A). Cryonecrosis effect and/or reduction of the tumor mass by cryosolidification was the objective. In the other group, cryosurgery was used as a pre-operative procedure with or without radiation and chemotherapy (Group B). Results were significantly better in group B than in the group A.
耳鼻咽喉科臨床学会の論文