BLM-Iontophoresis療法を行った舌癌における三重複癌の1例--頭頚部悪性腫瘍と三重複癌に関する文献的考察

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A case of triple cancer in a 66-year-old woman which included cancer of the tongue is reported. The first cancer was squamous cell carcinoma of the uterine cervix and treated by irradiation at 61 years of age in 1974. Then ovarian cancer, a rare so-called malignant Brenner tumor, and cancer of the tongue were found at the same time in 1979. The ovarian tumor of a size larger than a child's head was extirpated successfully. The pathological finding of the tongue specimen revealed that it was superficial squamous cell carcinoma, so that the patient received repeated local treatment by means of Bleomycin-Iontophoresis. Following this therapy which was given ten times in 30 days, good results were shown in both clinical and pathological findings.Although triple cancer in the head and neck region have been considered to be fairly rare, we found 45 cases in the past literature. It was suggested that such cases as well as double cancers were definitely increasing in recent years. A possible oncogenesis of multiple cancer in the head and neck region was discussed briefly.
耳鼻咽喉科臨床学会の論文