Clinical evaluation of AA-673 (amlexanox) tablets in perennial allergic rhinitis.

概要

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The therapeutic effects and safety of AA-673 tablets were studied in 67 patients with perennial allergic rhinitis at 9 institutions. The patients were generally prescribed a 50 mg tablet of AA-673 three times daily for at least 4 weeks.Evaluation of the final global improvement revealed "moderate to marked improvement" in 53% of the patients, and "slight to marked improvement" in 85%. Subjective improvements of sneezing attack, nasal discharge and nasal obstruction were noted in 38%, 31% and 36% of the patients, respectively.Side effects observed in 7 patients (10.4%), were all mild and transient. AA-673 tablets were considered to be effective for the treatment of the perennial allergic rhinitis.
耳鼻咽喉科臨床学会の論文