Radium Therapy for Carcinoma of the Tongue

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Results of radium therapy with or without multi-disciplinary treatment for carcinoma of the tongue were studied in 117 patients treated from 1973 to 1981 at Gunma Cancer Center.1. The patients were classified according to the TNM classification of UICC (1978). Seventeen patients were T1, 42 were T2, 31 were T3, 27 were T4, 92 were NO, 18 were N1, 2 were N2 and 5 were N3.2. The treatment methods included external irradiation with 1, 000-2, 000 rads by 6MV X-ray followed by radium interstitial implants of 6, 000-8, 000 rads in 93 patients (73.9 per cent), radium therapy with additional Bleomycin 45-60mg in 24 patients (20.5 per cent), and cryosurgery in 3 patients.3. The five year survival rate was 41.6 per cent; 100.0 per cent for T1, 50.0 per cent for T2, 38.8 per cent for T3 and 10.5 per cent for T4. The overall five-year cumulative survival rate was 46.9 per cent.For primary lesions of T3 or T4, greater efforts should be made with combined modalities, such as planned multi-disciplinary treatments with combined radiation and major surgery.
耳鼻咽喉科臨床学会の論文