URINARY EXCRETION OF THIAMINE PROPYL DISULFIDE-S35 AFTER ADMINISTRATION
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概要
- 論文の詳細を見る
1. Urinary excretion of S35 from the propylmercapto group after subcutaneous, intravenous or oral administration of TPD-S35(outer) was studied and S35 was shown to be excreted in the urine in large quantities (about 70% on the first day).2. The majority of S35 was excreted in the urine in the form of sulfate after administration of TPD-S35(inner).3. When TPD-S35(inner) was given intravenously, urinary excretion of thiamine was delayed compared with that in the case of thiamine-S35 and prolonged retention in the body was noted.4. With oral administration of TPD-S35(inner), urinary excretion of thiamine was far greater than that in the case of thiamine-S35.5. Urinary metabolites after administration of TPD-S35(inner) and thiamine-S35 in rabbits were examined and no compounds other than thiamine was detected.
- 日本ビタミン学会の論文
著者
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糸川 嘉則
Department Of Hygiene Faculty Of Medicine Kyoto University
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笹川 祐成
Department of Hygiene, Faculty of Medicine, Kyoto Univeristy
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藤原 元典
Department of Hygiene, Faculty of Medicine, Kyoto Univeristy
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池田 幸
Department of Hygiene, Faculty of Medicine, Kyoto University
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