A case report of cryoglobulinemia required amputation of toes.

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The patient was a seventy-year-old woman, who was admitted in our department for the purpose of treatment for her posttraumatic gangrene of the left first toe.On admitting examination, we did not find anything unual, but accentuation of erythrosedimentation-ratio and ascention of value of fibrinogen. We amputated the gangrened first toe. Although we intended to follow her, she had not visited. After one year, we amputated her second toe which showed a gangrene at that time.Afterwards we followed her attentively.About 2 months later, we noticed precipitation in her plasma and found purpura and ulceration at the periphery of the extremities. As a result of the detailed examination, we realized that she suffered from cryoglobulinemia.This disease must be differentiated without fail when we see a gangrened toe.
西日本整形・災害外科学会の論文