フグの炎症急性期における好塩基球遊走〔英文〕

概要

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Patterns of leucocyte infiltration during acute inflammation were investigated in puffer fish, with special reference to the migration of basophils, which are extremely abundant in puffers. Following subcutaneous injection of 1% λ-carrageenan solution, a large number of basophils as well as neutrophils infiltrated acutely within 24h. Basophil counts showed a tendency to decrease, while migration of the monocytes and macrophages might have continued throughout the chronic phase of inflammation. These results suggest that the basophils may have an important role in the acute phase of inflammation, although their functioning is not well understood. Blood basophils showed a more rapid increase than that in the inflammatory lesion, suggesting the existence of chemical mediators concerned with basophil proliferation.
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