アマジに対する核酸関連物質およびトリプトファン関連物質の摂餌刺激活性

概要

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The feeding stimulant activities of nucleotides-related and tryptophan-related componunds were tested on young jack mackerel Trachurus japonicus at concentrations of 1 and 5 mmol/100g dry diet, respectively. Effective doses of inosine 5'-monophosphate (IMP) and L-tryptophan (Trp) added to the diet on feeding activity were also examined. Of 33 compounds tested, IMP, guanosine 5'-monophosphate (GMP), uridine 5'-mono-phosphate (UMP), UDP, UTP, and Trp were effective. Hipoxanthine, nucleosides (inosine, adenosine, guanosine, uridine), nucleotides including adenosine 5'-monophosphate (AMP), ADP, ATP, IDP, ITP, GDP, GTP, xanthosine 5'-monophosphate, 3'-IMP, 3'-UMP, 2-deoxy-IMP, allyltio-IMP, and Trp-related compounds (D-Trp, DL-Trp, 5-hydroxy-Trp, 5-methyl-DL-Trp, tryptamine, 5-hydroxy-tryptamine, indolepropionic acid, indole-3-pyruvic acid, β-indolelactic acid, indole) were all ineffective. These results suggest that the molecular structure of 6-hydroxy-or 2-amino-6-hydroxy-purine riboside-5-phosphate is required for feeding stimulation toward jack mackerel, and that the activity of Trp was lost by a chemical modification of the molecule. The minimum concentrations of IMP and Trp needed to show the maximum effect were estimated as 0.8 and 5 mmol/100g dry diet, respectively.
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