TUM-N未使用結核患者から分離した結核菌のTUM-Nに対する感受性について : TUM-Nの耐性検査濃度設定のために

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Decrease of potency of TUM-N in Ogawas media and sensitivity to TUM-N of twenty-eight strains of tubercle bacilli isolated from sputa of the patients who have never used TUM-N were studied to decide the suitable concentrations for resistance test to TUM-N.<BR>(1) Potency of TUM-N is decreased from about one tenth to one seventh in Ogawas media compared with that in Kirchners agar media with 10% serum.<BR>(2) When the resistance tests to TUM-N are carried out by the absolute concentration method using Ogawas media, three concentrations, that is, 25mcg, 50mcg and 100mcg per ml are recommended. And it is thought that the resistance may be decided by growth on Ogawas media containing 100mcg/ml.
日本結核病学会の論文