Experimental and clinical study of the influence by metal and mandibular bone in radiofrequency capacitive hyperthermia.

概要

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To introduce radiofrequency hyperthermia delivered through HEH 500 C (13.56 MHz) on head and neck tumors, especially on oral cancer, an experimental study has been made as to the effect of RF waves on metals and mandibular bone in the phantom circumference. As a result, it was found that heated hot spots around both distal edges of metal were recognized in thermal video image when any metal was placed in a vertical situation, but there was only a little effect when the metal is placed in parallel between applicators.<BR>When dry mandibular bone was placed between applicators, almost same temperatures were measured at both internal and external sites of the bone in phantom.These, results show that radiofrequency hyperthermia will be able to make suitable heat even metals and bone exist between applicators.<BR>On a clinical trial, a case of non-measurable residual carcinoma of the floor of the mouth underwent 6 sessions of hyperthermia combined with irradiation as 4 preoperative treatment. The mandible which had been reconstructed by A-O plate at previous surgery revealed a partial response after treatment.The interruption by both metal and mandibular bone to gain 4 suitable intratumoral temperature higher than 42.5 degree C was fortunately small.
社団法人日本口腔外科学会の論文