Etiological studies of anomalous arrangement of the pancreatico-biliary ductal system and its clinical implications.

概要

論文の詳細を見る
In order to clarify the morphological criteria of anomalous arrangement of the pancreatico-biliary duct system, ninety-three patients whose junction of the pancreatic duct and common bile duct located in the extramural portion of the duodenum were investigated. The present study suggested that this anomaly results either from embryonic failure of the confluence of both ducts before 4 week gestation or from arrest of the migration of the choledocho-pancreatic junction inward the duodenal lumen after 8 week gestation. In 91 of the 93 patients their characteristic cholangiographic appearance implicated the former etiology. In 26 of the 91 patients the terminal bile duct joined with the secondary or more peripheral branches of the pancreatic duct and in the others it entered directly to the duct of Wirsung. Seventy-seven of the 91 were accompanied with congenital dilatation of the common bile duct and all of the remaining had normal bile duct. Only two patients had congenital biliary atresia, development of which might be based on the latter hypothesis.
財団法人日本消化器病学会の論文