タイトル無し

概要

論文の詳細を見る
Clinical investigation of group I pepsinogen (PG I) was carried out by PG I radioimmunoassay kit (Midori Juji). The mean (±SEM) levels of PG I in 318 healthy subjects was 79±3ng/ml. Mean serum PG I for the men in this population, 87ng/ml, was significantly greater than the value for women, 72ng/ml. Serum PG I levels in patients with gastric ulcer, and duodenal ulcer were 91±7ng/m1, 117±l0ng/ml, respectively, and both values were significantly greater than the value in subjects with endoscopically normal gastric mucosa, 63±5ng/ml. No significant change in serum PG I was observed after subcutaneous injection of tetragastrin or meal ingestion. A significant correlation was found between serum PG I and stimulated pepsin output (S.P.O.), peak pepsin output (P.P.O.), maximal acid output (M.A.O.), peak acid output (P.A.O.), which suggests that the level of serum PG I may be determined by chief cell mass.
財団法人日本消化器病学会の論文