STUDY ON GASTRIC ACID SECRETION IN DUODENAL ULCER:Part II: Relationship between Gastric Acid Secretion and the Recurrence of Duodenal Ulcer

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Fifty-seven patients with duodenal ulcer were divided into two groups with endoscopic follow-up study: one is the recurrent groups (35 cases) assuring the recurrence of duodenal ulcer and another is the non-recurrent group (22 cases) not assuring the recurrence of duodenal ulcer. Gastric analysis was examined to all of them in the two different stages (active and healed) under stimulation of AOC-tetragastrin 4γ/kg i.m.The results were as follows.1) In the active stage BAO of the recurrent group was higher significantly than that of the non-recurrent group but in the healed stage BAO of both groups decreased and there was no significant difference between both groups.2) In the active stage MAO of both groups was high and there was no significant difference between both groups but in the healed stage, though MAO of the non-recurrent group clearly decreased, that of the recurrent group was kept in high level.3) We would propose [BAO/MAO_??_40%] and [BAO_??_7.5mEg/h] as criteria of the recurrent group and [BAO/MAO_??_15%] as a criterion of the non-recurrent group.We concluded that continous high BAO and high MAO in the healed stage were concerned to the recurrence of duodenal ulcer.
財団法人日本消化器病学会の論文