ENDOSCOPIC PANCREATIC PARENCHYMOGRAPHY:Clinical Comparison of Two Contrast Agents

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We have been using endoscopic pancreatic parenchymography for diagnosing pancreatic diseases. On this occasion two water soluble contrast media, i.e. Sodium & Meglumine Diatrizoate and Sodium Iothalamate, were utilized in this method and a comparative study was made of the pancreatic parenchymographic result obtained with each contrast medium.With Sodium Iothalamate, a natrium salt preparation, good opacification of the pancreas was obtained in about 92% of the cases, but with Sodium & Meglumine Diatrizoate, only in 33%. Natrium salt preparation seems to be an apropriate contrast medium for this method on the assumption that it may have higher pancreatic permeability than Methylglucamine salt preparation. No particular complications were experienced in the 93 cases submitted to this method.On injecting the contrast media, few cases complained of abdominal pain which was, however, only transient. Although the serum amylase level rose in about 60% of the cases, no cases were presumed to have caught acute pancreatitis clinically.
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