女子従業員の血中鉛量とALA⋅D活性に関する一考察 : 鉛取扱い作業者と比較して

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δ-aminolevulinic acid dehydrase (ALA⋅D) activity and lead in blood concentration (Pb-B) were measured during health examination for women workers, as a control of lead exposed workers.Pb-B of 144 women workers without occupational exposure to lead ranged between 6.1 and 13.5μg/dl but that of 165 lead exposed workers was from 6.9 to 38.5μg/dl. On the other hand, ALA⋅D activity in all women ranged widely between 0.43 and 1.52 units while that of the lead exposed workers was from 0.1 to 1.2 units. The lowest value found in the activity of ALA⋅D in the women group corresponded to the peak of that in the lead exposed workers group.The result of our findings was related to the effect of age for ALA⋅D activity showed a tendency to decrease from the fifties and its activity of the age group under 20 years was higher than other age groups. Therefore, the trend was evaluated by statistical method with Students t-test. Consequently, when the mean values of ALA⋅D activities were compared with both groups at the same levels of Pb-B, the values of the lead exposed workers group was found to be lower from 0.34 to 0.4 units than the womens group. Closed negative correlation between Pb-B and ALA⋅D showed to be over 15μg/dl of Pb-B levels
日本衛生学会の論文