Effects of CB-154 (2-Br-α-Ergocryptine) on Prolactin and Growth Hormone Release in an Acromegalic Patient with Galactorrhea
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概要
- 論文の詳細を見る
An acromegalic patient with galactorrhea was treated with an ergot alkaloid, 2-Br-α-ergocryptine (CB-154). Serum prolactin decreased rapidly to normal level by CB-154 and the complete cessation of galactorrhea was noted. The inhibitory effect of CB-154 on growth hormone (GH) release was also noted, but slight. The mechanism of inhibitory action of CB-154 on both prolactin and GH secretion was discussed in connection with the experimental model of pituitary tumors, in which both hormones were produced by a single type of tumor cells. The discontinuation of CB-154 treatment was associated with the return of both prolactin and GH levels to the initial high values with resumption of galactorrhea.
- 社団法人 日本内分泌学会の論文
著者
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Aono Toshihiro
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Yamasaki Masato
Department Obstetrics And Gynecology Osaka Rosai Hospital
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Sato Yasuko
Department Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
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Ueda Gaiko
Department Of Obstetrics And Gynecology Okayama University Medical School
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Kurachi Keiichi
Department Of Obstetrics & Gynecology Osaka Medical School
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SHIOJI TAKENORI
Department of Obstetrics and Gynecology, Osaka University Medical School
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Sato Yasuko
Department Of Gynecology The Center For Adult Diseases
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KURACHI KEIICHI
Department of Gynecology and Obstetrics, Osaka University, Medical School
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