Sodium Induces Oxytocin Release from Superfused Rat Pituitary
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概要
- 論文の詳細を見る
The effects of various osmotic agents on the release of oxytocin were examined in a superfusion system. Oxytocin was released significantly from the rat pituitary by superfusion with medium of an osmolality of 350mOsm/kg H<SUB>2</SUB>O adjusted with NaCl, regardless of the presence of the rat hypothalamus. Media adjusted to an osmolality of 350 mOsm/kg H<SUB>2</SUB>O with sucrose, glucose, urea or mannitol had no effect on oxytocin release from the hypothalamo-pituitary complex. Medium containing excess Na<SUB>2</SUB>SO<SUB>4</SUB> induced significant release of oxytocin from the pituitary without the hypothalamus. The administration of tetraethlyammonium chloride had no oxytocin secretion. These data suggest that oxytocin release from the pituitary is influenced by the level of sodium ion rather than the osmotic pressure.
- 社団法人 日本内分泌学会の論文
著者
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Aono Toshihiro
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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KURACHI Keiichi
Department of Obstetrics and Gynecology, Osaka University Medical School
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Sakumoto Tetsuro
Department Of Neuroanatomy Osaka Medical School
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MIYAKE AKIRA
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Tasaka Keiichi
Department Of Obstetrics And Gynecology Faculty Of Medicine Osaka University
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Kurachi Keiichi
Department Of Obstetrics & Gynecology Osaka Medical School
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KAWAMURA YASUHIRO
Department of Obstetrics and Gynecology, Osaka University Medical School
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Miyake Akira
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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MIYAKE AKIRA
Department of Obstetrics and Gynecology, Osaka University Medical School
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KURACHI KEIICHI
Department of Gynecology and Obstetrics, Osaka University, Medical School
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SAKUMOTO TETSURO
Department of Obstetrics and Gynecology, Osaka University Medical School
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