Effect of Bordetella Pertussis Vaccine on Glucagon Secretion in Normal and Alloxan Dogs

スポンサーリンク

概要

• 論文の詳細を見る

• The effect of Bordetella pertussis vaccine on plasma glucose, insulin and glucagon secretion was investigated in normal and alloxan dogs. On the 8th day after the vaccine injection, in normal and alloxan dogs during the infusion of arginine and glucose, the plasma glucose level was lower and the IRI level was higher than in the saline controls. On the other hand, the plasma IRG level showed no significant difference between the vaccine and saline control groups of normal dogs, but in alloxan dogs this vaccine made the plasma IRG level lower during arginine infusion than in the saline controls and suppressed it significantly during glucose infusion.These effects of the vaccine disappeared on the 30th day after its injection into normal and alloxan dogs.<BR>It is suggested that in normal dogs Bordetella pertussis vaccine decreased plasma glucose through the promotion of insulin secretion without any effect on glucagon secretion, while in alloxan dogs this vaccine might alleviate hyperglycemia through the enhancement of insulin and the inhibition of glucagon secretion.

• 社団法人 日本内分泌学会の論文

著者

• Kondo Motoharu

  First Department Of Internal Medicine Department Of Radiology Kyoto Prefectural University Of Medici

• Yoshida Toshihide

  First Departmen T Of Internal Medicine Kyoto Prefectural University Of Medicine

• ARAKI YOSHIMASA

  First Department of Internal Medicine, Kyoto Prefectural University

• NAKAMURA YOSHIO

  First Department of Internal Medicine, Kyoto Prefectural University

• Nakamura Yoshio

  Department Of Artificial Kidney Matsushita Memorial Hospital

• OSUMI TAKAKO

  First Department of Internal Medicine, Kyoto Prefectural University of Medicine

関連論文

• Pharmacological Studies of Alcohol Susceptibility and Brain Monoamine Function in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) and Stroke-Resistant Spontaneously Hypertensive Rats (SHRSR)
• Acute and Chronic Regulation of ob mRNA Levels by β_3-Adrenoceptor Agonists in Obese Yellow KK Mice
• Trp64Arg Mutation of β_3-Adrenergic Receptor and Non-Insulin Dependent Diabetes Mellitus
• Octreotide and Bromocriptine Suppress Thyroid Hormone Levels and Thyroid Nodule in an Acromegalic Patient with Nontoxic Autonomous Goiter
• Effect of CL316, 243, a Highly Specific β_3-Adrenoceptor Agonist, on Lipolysis of Epididymal, Mesenteric and Subcutaneous Adipocytes in Rats
• A case of primary hyperparathyroidism that had been treated under a diagnosis of depression for 10 years
• BETA-3 ADRENERGIC AGONIST, BRL-26830A, AND ALPHA/BETA BLOCKER, AROTINOLOL, MARKEDLY INCREASE REGIONAL BLOOD FLOW IN THE BROWN ADIPOSE TISSUE IN ANESTHETIZED RATS
• ACTH expression in synovium of patients with rheumatoid arthritis and Lewis rats with adjuvant arthritis
• HYPERPLASIA OF BROWN ADIPOSE TISSUE AFTER CHRONIC STIMULATION OF β3-ADRENERGIC RECEPTOR IN RATS
• von Recklinghausen's Disease with Hyperthyroidism
• Expression of β3-Adrenoceptor and Stimulation of Glucose Transport by β3-Agonists in Brown Adipocyte Primary Culture^1
• Chronic administration of β-Adrenergic Agonists Can Mimic the Stimulative Effect of Cold Exposure on Protei Synthesis in Rat Brown adipose Tissue
• A case of a flare-up of systemic lupus erythematosus and Sjogren's syndrome manifesting with cholecystitis secondary to pregnancy
• Pyogenic Clavicular Osteomyelitis Associated with Disseminated Intravascular Coagulation and Acute Renal Failure in a Patient with Non-Insulin-Dependent Diabetes Mellitus
• Involvement of Lipid Peroxidation in Free Fatty Acid-Induced Isolated Rat Pancreatic Acinar Cell Injury
• Circulating immune complexes in patients with collagen vascular diseases complicated with pulmonary fibrosis
• -0420-ISCHEMIC THRESHOLD FOR THE PRESERVATION OF MYOCARDIAL CONTRACTILITY AND GLUCOSE METABOLIC ACTIVITY IN PATIENTS WITH PRIOR MYOCARDIAL INFARCTION
• -496-THE RELATIONSHIP BETWEEN RESIDUAL MYOCARDIAL BLOOD FLOW AND CARDIAC WALL MOTION ABNORMALITIES IN PATIENTS WITH MYOCARDIAL INFARCTION : Myocardial Infarction : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE
• Tooth Pulpal Nociceptors in the Rat Lower Incisor, An In vitro Study
• Comparison of Atypical /33-Adrenoceptor Agonists With Their Respective Metabolic Activities in Rat White Adipocytes
• Effect of Acetylcholine on The Secretion of Gut Glucagon Immunoreactivity and Gut Glucagon-Like Immunoreactivity in Pancreatectomized Dogs
• The Effect of Hypophysectomy and Hypophysis-Transplantation on The Secretion of Gut Glucagon Immunoreactivity and Gut Glucagon-Like Immunoreactivity in Depancreatized Dogs
• Effect of Islet-Activating Protein (IAP) Upon Insulin Secretion from Human Pancreatic Islets
• The Insulin Secretion of a Minced Neonatal Rat Pancreas Cultured in a Pancreatic Chamber, in Response to Various Insulin Secretagogues
• Normalization of Blood Glucose in Totally Pancreatectomized Dogs by Use of Pancreatic Chambers
• Effect of Bordetella Pertussis Vaccine on Glucagon Secretion in Normal and Alloxan Dogs
• Antioxidant Therapy in Digestive Diseases
• Antioxidative Effects of a Processed Grain Food.
• Chronic Administration of .BETA.-Adrenergic Agonists Can Mimic the Stimulative Effect of Cold Exposure on Protein Synthesis in Rat Brown Adipose Tissue.
• .BETA.3-Adrenergic Agonist Up-Regulates Uncoupling Proteins 2 and 3 in Skeletal Muscle of the Mouse.
• Expression of .BETA.3-Adrenoceptor and Stimulation of Glucose Transport by .BETA.3-Agonists in Brown Adipocyte Primary Culture.

もっと見る 閉じる

スポンサーリンク