DDQ酸化で除去できるメトキシベンジル (MPM) 保護基
スポンサーリンク
概要
- 論文の詳細を見る
Methoxybenzyl (MPM) protecting groups for hydroxy function were readily and efficiently removed with DDQ in CH<SUB>2</SUB>Cl<SUB>2</SUB>-H<SUB>2</SUB>O at room temperature. Under these neutral conditions, other usual protecting and functional groups remained unchanged. Dimethoxybenzyl (DMPM) groups were more reactive than MPM with DDQ. This article deals not only with the deprotection of MPM and DMPM with selectivities among MPM, DMPM, benzyl groups, and other groups, and with some extensions such as intramolecular oxidative and kinetic acetalizations, but also with some applications in the synthetic study of macrolide and polyether antibiotics from D-glucose.
- 社団法人 有機合成化学協会の論文
著者
関連論文
- An Application of Reactions of β-Ketosulfoxides to Estrone Synthesis
- 33 ケトスルホキサイドを利用した合成研究 : Olivacine,Ellipticine,Estroneの合成
- 薬学での大学院改革の考え方
- 17 マクロリドのキラル合成 : 3.エリスロノリドAの全合成研究(その2)
- Photochemical Synthesis of 1,2,3,4-Tetrahydroisoquinolin-3-ones and Oxindoles from N-Chloroacetyl Derivatives of Benzylamines and Anilines. Role of Intramolecular Exciplex Formation and cis Conformation of Amide Bonds
- Reactions and Synthetic Applications of β-Keto Sulfoxides. X. Synthesis of Ellipticine Analogs modified at the 5-Position
- PHOTOCHEMICAL SYNTHESIS OF ANTITUMOR PLATINUM PYRIMIDINE GREENS ; POSSIBLE CONTRIBUTION OF SINGLET OXYGEN(Communications to the Editor)
- 薬学生の就職
- 光学活性な天然ホスト分子としてのポリエーテル抗生物質
- Highly Stereoselective Total Synthesis of Tylonolide, the Aglycon of the 16-Membered Macrolide Antibiotic Tylosin. II. Total Synthesis of Tylonolide by Virtue of 4-Methoxybenzyl and 3,4-Dimethoxybenzyl Protection(Organic,Chemical)
- Highly Stereoselective Total Synthesis of Tylonolide, the Aglycon of the 16-Membered Macrolide Antibiotic Tylosin. I. Construction of the C-1-C-8 Chiral Centers(Organic,Chemical)
- Highly Stereoselective Total Synthesis of Methynolide, the Aglycon of the 12-Membered Macrolide Antibiotic Methymycin. II. Kinetic Acetalization and Synthesis of the Seco-Acid(Organic,Chemical)
- On a Novel System for the Photosensitized Water Reducaion Which Contains the Iron-Sulfur Cluster, (Et_4N)_2 [Fe_4S_4 (SBzl)_4]
- 太陽光エネルギーの化学エネルギーへの変換 : 有機光化学の立場から
- Photoalkylation of Aromatic Amino Acids as a Model of Photochemical Modification of Protein with Chloroacetamide
- Photocyclization of N-Chloroacetyl-2,5-dimethoxyphenethylamine. Synthesis of Pyrroloindoles
- Cage Effect for the Photochemical Formation of the Ten-Membered Lactam from N-Chloroacetyl-3-methoxyphenethylamine
- 上田亨先生を偲んで
- マクロリド, ポリエーテル抗生物質の立体選択的合成研究
- DDQ酸化で除去できるメトキシベンジル(MPM)保護基
- 58 マクロリドのキラル合成 : 4. メチノリドの全合成
- メルドラム酸の化学 : マロン酸エチルとの違いをとらえる
- Meldrum's Acid in Organic Synthesis. V. Versatile One-pot Synthesis of Indolepropionic Esters via Simultaneous Condensation of Three Different Carbon Components, Indole, Aldehydes and Meldrum's Acid
- 電子移動光化学反応
- 84 マクロライドのキラル合成 : 1. Tylonolide,Protylonolide及びMycinolide全合成を目的としたMethynolideの合成
- Synthesis of 12α and 12β-Carboxyestradiol Derivatives via the Thermal Elimination of β-Ketosulfoxide
- 米光宰会頭に聞く
- マクロリド合成
- マクロリドの合成 : 高い選択性と効率をもった易しい合成法を確立するために
- DDQ酸化で除去できるメトキシベンジル (MPM) 保護基
- 4 インドール側鎖の選択的酸化による酸化型ジケトピペラジン系アルカロイドの合成
- A Convenient Synthesis of Estrone and 11-Methylequilenines based on the Thermal Elimination of β-Ketosulfoxides
- 日本薬学会学術賞紹介 : -2 井下田浩氏の業績
- Photocyclization of N-Chloroacetyl-3-methoxyphenethylamine and N-Chloroacetyl-3,5-dimethoxyphenethylamine.
- Selective Reduction of Peptide-ester Groups in Aqueous Solution III. Valine and Proline Esters
- Esterification of Model Peptides in Aqueous Solution