EFFECT OF TEMPERATURE ON THE AUTOLYSIS OF COLD-STORED HUMAN PLACENTA

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According to Filatov et al. (1, 2, 3) there will originate the so-called biogenic stimulant, if the tissue of animal or plant is exposed to the cold circumstance sublethally. But the chemical properties of biogenic stimulant remain still entirely unknown, thoughh the chemists in Soviet Union tend to mention some kinds of organic acids, amino acids, nucleic acids, and some of vitamine B group as its chemical components. In our institute the "Placenta Plasma" (4), the suspension of cold-stored human placenta in the normal saline solution, has been studied and we are forced to believe that the placenta plasma has a wide range of usefullness to the deseases. So, in order to determine the chemical nature of what is called as the biogenic stimulant, the present authors intend to investigate what kinds of substances are newly appeared and disappeared in or from the original placenta during a course of storage in the cold situation. In the previous paper (5) we published on the concentration of hydrogen ion and of the various nitrogen fractions. From these data it was supposed that the autolysis of tissue progressed considerably even under the cold circumstance of about 2-4°C. Those values measured, however, were fairly fluctuatad by the conditions of temperature and others. So, it is an inevitable necessity to follow the progress of autolysis under the coldness of various temperature.
久留米大学医学部 The Kurume Medical Journal 編集部の論文