Clinical and Pathological Evaluation of Early Gastric Cancer and Lymph Node Metastasis

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Four hundred fifty-nine solitary early gastric cancers were studied, retrospectively. There were 313 men and 146 women. The proportion for solitary early gastric cancer of the total gastric cancers was 23.4% (459/1960). Early cancers were grossly divided into three fundamental types. One hundred nine cancers (23.7%) were the elevated type, 8 cancers (1.7%) were the flat type, and the depressed type was the most frequent, present in 342 of the patients (74.5%). Early cancers were also divided into two groups based on the depth of cancer invasion. Cancers confined to the mucosa, m-cancers, were observed in 220 patients (47.9%), whereas cancers invading the submucosa, sm-cancers, were seen in 239 patients (52.1%). On microscopic examination, 329 cancers (71.7%) were the differentiated type and the remaining 130 cancers (28.3%) were the undifferentiated type. Positive lymph node metastases were noted in 48 of 459 patients, which is a lymph node metastasis rate of 10.4% . With m-cancers, only 4.1% (9/220) had lymph node metastases. On the other hand, in sm-cancers, 16.3% (39/139) had lymph node metastases (P<0.001) . The 5-year and 10-year survival rates were 96.8% and 96.8 % in m-cancer, and 94.8% and 90.1% in sm-cancers. The survival rates for differentiated land undifferentiated types of cancers were not significantly different.
久留米大学医学部 The Kurume Medical Journal 編集部の論文