Cyfra 21-1 as a Marker of Lung Cancer.
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概要
- 論文の詳細を見る
The utility of cytokeratin fragment (Cyfra) 21-1, a new tumor marker, was investigated in 100 patients with lung cancer. Sandwich enzyme immunoassay detected Cyfra 21-1 in the sera of 60% of patients. Sensitivity of this marker was especially high (86.4%) for squamous cell carcinoma, exceeding that of a similar marker, squamous cell carcinoma antigen (SCC, 54.5%). In contrast, sensitivity of Cyfra 21-1 was relatively low for adenocarcinoma (52.6%) and for small cell carcinoma (50%). We conclude that Cyfra 21-1 is of value in diagnosis of lung cancer, particularly squamous cell carcinoma.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Watanabe Hisashi
Department of Cardiology, The Jikei University School of Medicine
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OIZUMI Kotaro
Department of Internal Medicine, Kurume University
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Kinoshita Masaharu
Department of Applied Physics, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan
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RIKIMARU TORU
Department of Medicine, Kurume University School of Medicine
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SUMITA SHINYA
Department of Medicine, Kurume University School of Medicine
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ICHIKI MASAO
Department of Medicine, Kurume University School of Medicine
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KINOSHITA MASAHARU
Department of Medicine, Kurume University School of Medicine
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OKUBO YO
Department of Medicine, Kurume University School of Medicine
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WATANABE HISASHI
Department of Medicine, Kurume University School of Medicine
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MATSUNAMI MICHIYA
Department of Medicine, Kurume University School of Medicine
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FURUNO HIROAKI
Department of Medicine, Kurume University School of Medicine
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SHIRAISHI TSUNEAKI
Department of Medicine, Kurume University School of Medicine
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