肝細胞癌のリンパ節転移とその特徴-胆管細胞癌を対照とした日本病理剖検輯報の集計-

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A statistical analysis was performed on lymph node metastases of hepatocellular carcinoma (HCC) comparing to cholangiocellular carcinoma (CCC), refering to annual of the pathological autopsy cases in Japan for 10 years (1972-1981). In 12459 cases of HCC and 2048 of CCC, the ratio of lymph node metastases were 33.3% and 67.6% (p<0.01), respectively. The ratio of hematogenous metastases and dissemination were 74.2% and 81.9% (p<0.01). As to HCC and liver cirrhosis (LC), lymph node metastases were 24.6% of HCC with LC and 43.9% of HCC without LC (p<0.01), and hematogenous metastases and dissemination were 59.4% in the former and 78.6% (p<0.01) in the latter. Distant lymph node metastases accompanying no regional metastases were 42% of HCC and 34% of CCC. HCC, compared with CCC, tended to expand for more cranialis direction. However in a stage when lymph node metastases were limited in the regional nodes, direction of metastases in both HCC and CCC were more caudal.
社団法人日本肝臓学会の論文