THE EFFECT OF ALKYLBENZENESULFONAMIDE ON LANSING STRAIN VIRUS IN MICE

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概要

• 論文の詳細を見る

• Alkylbenzenesulfonamide was screened as to its effect in vitro and in vivo on Lansing strain virus. The relationship between activity and alkyl chain length of the above compounds are discussed.p-Methylbenzene-phenylsulfonamide was selected as the most effective among the series of alkylbenzenesulfonamide and p-methylbenzene-alkylphenylsulfonamide.This compound was effective on the Lansing strain in vitro and in vivo tests using mice.Its maximum effective concentration in in vitro test was 250 γ/ml and the optimum dose in the in vivo test was 12-14mg/kg by the intravenous administration.

• The Keio Journal of Medicineの論文

著者

• Toyoshima Shigeshi

  Pharmaceutical Institute Keio-gijuku University

• Ueda Takeo

  Pharmaceutical Institute Keio-gijuku University

• UEDA TAKEO

  Pharmaceutical Institute, School of Medicine Keio University

• TSUJI TADAKAZU

  Pharmaceutical Institute, School of Medicine, Keio University

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• THE EFFECT OF ALKYLBENZENESULFONAMIDE ON LANSING STRAIN VIRUS IN MICE

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