THE ANTIVIRAL EFFECT OF GUANIDINE AND ITS DERIVATIVES:V. ANTIVIRAL EFFECT OF ISONICOTINYLGUANIDINE AND NIOOTINYLGUANIDINE
スポンサーリンク
概要
- 論文の詳細を見る
To find antiviral agents, a lot of guanido group containing compounds were synthesized and screened as to their antiviral effect. Among these synthesized compounds, the two compounds, Isonicotinylguanidine and Nicotinylguanidine, were found to be effective on some of picorna viruses. The site of the action of Isonicotinylguanidine was found to be the inhibition of the early step of intracellular multiplication of virus.
- The Keio Journal of Medicineの論文
著者
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Toyoshima Shigeshi
Pharmaceutical Institute Keio-gijuku University
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Ueda Takeo
Pharmaceutical Institute Keio-gijuku University
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SETO YOSHIKO
Pharmaceutical Institute, Keio University
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TAKAGI KANAME
Pharmaceutical Institute, Keio University
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TAKAOKU MASAKO
Pharmaceutical Institute, Keio University
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