悪性リンパ腫患者の免疫能

概要

論文の詳細を見る
The immunocompetence of patients with malignant lymphoma was examined and compared to that of patients with cancer in head and neck. The following is a conclusion obtained.1) There was no aggravation of general condition in either patient before the treatment.2) Patients with malignant lymphoma did not show the elevation of serum Ig-G level and serum-inhibitory factors detected in patients with cancer. The increase of a2-globulin in patients with malignant lymphoma was not so significant as in patients with cancer. 3) The cellular immunocompetence in patients with malignant lymphoma was impaired more markedly than in patients with cancer. Number of peripheral lymphocyte was decreased much the same, but PPD skin test, PHA skin test and PHA-induced lymphocyte transformation test were suppressed more markedly in patients with malignant lymphoma.4) The depressed cellular immunocompetence in these two disease might be caused by different mechanism. It is strongly suggested that the humoral factors may play a role in patients with cancer and cellular factors in patients with malignant lymphoma for the depressed immunocompetence.5) In the treatment of patients with malignant lymphoma, follow-up examinations of immunocompetence are required and immunotherapy is more necessary than in patients with cancer.
社団法人日本耳鼻咽喉科学会の論文