鼻アレルギ-に対する鼻内噴霧用Beclomethasone dipropionateエアゾ-ル剤の二重盲検法による臨床的検討

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To objectively assess the effectiveness of SN 105, a double blind test was carried out jointly at 16 hospitals on 183 patients with a perennial nasal allergy. SN 105 or placebo was applied in one spray into the nasal cavity, four times daily to adults and twice daily to children of twelve and under, for two weeks. The results were as follows:SN 105 was significantly superior to placebo with degree to final global improvement rating, subjective and objective assessment and global utility rating with no relation to factors such as sex, age, type, severity, duration of the disease and the allergen involved.The effect of SN 105 was initiated in 78% within one week and was maintained for at least one week after discontinuation.Side effects induced were minimum without any significant difference between the two groups. Adreno-cortical inhibition was not observed.
耳鼻咽喉科臨床学会の論文