リウマチ性疾患による慢性喉頭気管狭窄

概要

論文の詳細を見る
Two cases with chronic severe laryngo-tracheal stenosis due to rheumatic diseases were treated in our clinic during 8 years from 1970 to 1977. The first case, 48-year-old female, died in 1971, after one and a half year treatment. The second case, a 33-year-old female, is under treatment. When we performed tracheotomy, disappearance of the upper tracheal cartilages was observed and, in microscopic study of the residual tracheal cartilages, many collagen fibers were found by H.E. staining together with degeneration or absorption of hyaline cartilage in both cases. Laryngeal examination showed ankylosis of the cricoarytenoid joint in both cases. In the first case, abnormal findings were obtained in X-ray examination of the breast suggesting Tietzes syndrome and, at autopsy, marked wrinkle formation and stenosis of the trachea and main bronchus were observed the appearance of which resembled the esophageal lumen. In microscopic observation, columnar tracheal epithelium was found to change to the squamous epithelium with keratinization. The first case had a history of RA and the second was diagnosed to be a typical case of RA, based on the ARAs classification.
社団法人日本耳鼻咽喉科学会の論文