Follow Up Study on the Changes in the Clinical Features and Prognosis of Japanese Patients with Systemic Lupus Erythematosus During the Past 3 to 4 Decades
スポンサーリンク
概要
- 論文の詳細を見る
Seven hundred and fifty four Japanese SLE patients were subdivided into the following 3 groups according to the year of diagnosis : Group A ; 85 cases between 1955 and 1969, Group B ; 322 cases between 1970 and 1979 and Group C ; 347 cases between 1980 and 1990. The clinical features and prognosis were compared among the 3 groups. The number of SLE patients with persistent and/or profuse proteinuria, psychosis, unconsciousness, thrombocytopenia and other disorders in Group C was less than that of Groups A and/or B. The number of cases treated with steroids, immunosuppressants, non-steroidal antiinflammatory drugs, antihypertensive drugs in Group C was less than that of Groups A and/or B. However, the number of cases treated with pulse therapy and plasmapheresis in Group C was more than that of Groups A and/or B. The mortality rate of SLE, especially due to uremia, significantly decreased from Group A to Group C. Five-year and 10-year survival rates in Group C were 95.2% and 93.4%, respectively, revealing a significantly more favorable prognosis than that of the other groups. J Epidemiol, 1993; 3:19-27.
- 日本疫学会の論文
著者
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ISOBE Yukio
Department of Applied Chemistry & Chemical Engineering, Faculty of Engineering, Yamaguchi University
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Hirose Shunichi
Department Of Electrical Engineering Nagoya University
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Tokano Yoshiaki
Department Of Internal Medicine And Rheumatology Juntendo University School Of Medicine
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Hashimoto Hiroshi
Department Of Adult Disease Jr Tokyo General Hospital
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Sugawara Masahiro
Department Of Rheumatology And Internal Medicine Juntendo University
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Takasaki Yoshinari
Department of Internal Medicine and Rheumatology
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Sakamoto Mitsutaka
Department of Internal Medicine and Rheumatology
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Kabasawa Kazuyuki
Division of Information Science Central Laboratory of MedicalSciences, Juntendo University, School of Medicine
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Isobe Yukio
Department of Internal Medicine and Rheumatology
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Sugawara Masahiro
Department of Internal Medicine and Rheumatology
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Tokano Yoshiaki
Department of Internal Medicine and Rheumatology
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Takasaki Yoshinari
Department of Internal Medicine
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Hashimoto Hiroshi
Department of Internal Medicine and Rheumatology
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