Pathologic Characteristics of Stroke and Myocardial Infarction in Japan:Akita Pathology Study
スポンサーリンク
概要
- 論文の詳細を見る
The Akita pathology study was conducted to examine risk characteristics of stroke and myocardial infarction, and trends of atherosclerosis in brain and coronary arteries. The subjects were 845 men aged 30 and over, examined among autopsied men admitted to a local hospital of northeast Japan between 1966 and 1984. The overall autopsy rate was 88%. Blood pressure and serum cholesterol at admission was compared according to type of stroke. To elucidate risk characteristics of myocardial infarction in Akita, the infarction cases were compared with those in Osaka (the second largest city in Japan). Grades of atherosclerosis for basal cerebral arteries and coronary arteries and grade of arteriosclerosis for intracerebral small arteries were determined blindly by one pathologist using a method of cross-sectional stenosis scoring. As expected, blood pressure levels were higher in all types of stroke than nonstroke. Serum cholesterol was lower in cerebral hemorrhage than in nonstroke, and was higher in infarction in cortical artery regions than in nonstroke. Cerebral hemorrhage showed the lowest proportion of significant stenosis in both basal and intracerebral penetrating arteries. Myocardial infarction in Akita had a higher prevalence of hypertension and a lower prevalence of high serum cholesterol, the higher proportion of scattered type of infarction (mostly subendocardial infarction) compared with myocardial infarction in Osaka. Age-adjusted mean scores for atherosclerosis in the coronary arteries and basal cerebral arteries declined 30% and 42%, respectively, between 1966-1974 and 1975-1984. There was a decline in age-adjusted blood pressure levels at admission: 10 mmHg for systolic and 4 mmHg for diastolic blood pressure, whereas mean serum cholesterol rose 6 mg/dl. There results indicated that hypertension and low serum cholesterol levels were associated with cerebral hemorrhage, and mostly hypertension with myocardial infarction in Akita. The deline in blood pressure levels between the 1960's and 1980's may have contributed to the decreased atherosclerosis in both brain and coronary arteries. The effect of an increase in serum cholesterol for coronary atherosclerosis was overwhelmed by the large decrease in blood pressure levels.
- 日本疫学会の論文
著者
-
Terao Atsushi
Department Of Preventive Cardiology National Cardiovascular Center
-
ISO Hiroyasu
Institute of Community Medicine, University of Tsukuba
-
Baba Shunroku
Department Of Preventive Cardiology National Cardiovascular Center
-
Shimamoto Takashi
Institute Of Community Medicine University Of Tsukuba
-
Konishi Masamitsu
Department Of Clinical Pharmacology And Therapeutics Tohoku University
-
Iida Minoru
Department Of Domestic Science Tokyo Bunka Junior College
-
Komachi Yoshio
Osaka Medical Center For Health Science And Promotion
-
Konishi Masamitsu
Department of Preventive Medicine, National Cardiovascular Center
-
Iida Minoru
Department of Epidemiology and Mass Examination for Cardiovascular Disease,The Center for Adult Diseases
関連論文
- Effects of Obesity and Smoking on Mental Stress-Induced Blood Pressure and Augmentation Index Responses in Normotensive Young Males : The J-SHIPP Study
- Comparison of the Prevalence of Asymptomatic Carotid Atherosclerosis Detected by High-Resolution Ultrasonography in Rural and Urban Middle-Aged Japanese Men
- Differences in Dietary Habits, Serum Fatty Acid Compositions and Other Coronary Risk Characteristics between Freshmen and Fourth-year Male University Students
- Long-Term Prognosis after Stroke : A Community-Based Study in Japan
- Impact of Anger Expression on Blood Pressure Levels in White-Color Workers with Low-Coping Behavior
- Validity and Reliability of the Japanese Version of the Selected Anger Expression Scale and Age, Sex, Occupation and Regional Differences in Anger Expression Among Japanese
- Plasma Fibrinogen, Tissue Plasminogen Activator, Plasminogen Activator Inhibitor 1, and Their Related Factors in Three Japanese Population Samples
- Trends for Cardiovascular Risk Factors and Diseases in Japan
- Epidemiology of Cerebrovascular Disease : Stroke Epidemic in Japan
- Lack of Association between Genetic Polymorphism of CYP11B2 and Hypertension in Japanese: The Suita Study
- Relationships between Lifestyle-Related Factors and Immune Parameters in Middle-Aged Male Workers
- The impact of the metabolic syndrome and its components on the incidence of ischemic heart disease and stroke : the Japan public health center-based study
- A Case-Reference Study on Plasma Fibrinogen Concentrations and Coronary Atherosclerosis in Japanese
- Changes in Cardiovascular Risk Factors Related with Menopause in Rural Japanese Women
- Trends for Coronary Heart Disease and its risk Factors in Japan : Epidemiologic and Pathologic Studies : 53th Annual Scientific Session of the Japanese Circulation Society
- The Trend of Coronary Heart Disease and Its Risk Factors Based on Epidemiological investigations : PANEL DISCUSSION ON MORTALITY AND MORBIDIRY TRENDS IN ACUTE MYOCARDIAL INFARCTION IN JAPAN AND EMERGENCY CARE FOR IT : 50th Annual Scientific Session of the
- -247- COMMUNITY BASED SURVEY OF ACUTE MYOCARDIAL INFARCTION DEATHS IN AREA : Ischemic Heart Diseases : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Anthropometric Measures, Blood Pressure and Major Laboratory Examination Results in the Health Check-up Examination among the JPHC Study Participants at Baseline Survey
- -229-A COMPARISON OF BLOOD PRESSURE IN PARENTS AND THEIR CHILDREN BASED ON THE DATA COLLECTED FROM LONG TERM OBSERVATION
- Recent Morbidity Trends in Myocardial infarction in Japan : investigation of Death Certificates and the Survival Rates At Coronary Care Units : PANEL DISCUSSION ON MORTALITY AND MORBIDIRY TRENDS IN ACUTE MYOCARDIAL INFARCTION IN JAPAN AND EMERGENCY CARE F
- -0251-EVALUATION OF BLOOD PRESSURE AT HEALTH CHECK-UP CLINIC BY AMBULATORY 24-HOUR BLOOD PRESSURE MONITORING ON USUAL WORKING DAY AND ECHOCARDIOGRAPHY
- RECENT CHANGES IN LIFESTYLE AND RISK FACTORS OF STROKE IN JAPAN : Valvular Heart Disease, Pulmonary Circulation : FREE COMMUNICATIONS (VI) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Health Status, Life Habits, and Social Background among the JPHC Study Participants at Baseline Survey
- Intake Ratio of Water-insoluble Dietary Fiber to the Water-soluble One in Japanese: An Estimation on Dietary Records and the Secular Consideration on the National Nutrition Survey
- Anthropometric Measures, Blood Pressure and Major Laboratory Examination Results in the Health Check-up Examination among the JPHC Study Participants at Baseline Survey
- Trends of Blood Pressure Distributions in a Northeast Rural Japanese Population
- Dietary Fiber Intake of Japanese Younger Generations and the Recommended Daily Allowance.
- FOUR CASES OF IDIOPATHIC RENAL HEMORRHAGE SUCCESSFULLY TREATED WITH TONSILLECTOMY AND ARTIFICIAL HIBERNATION THERAPY
- Physical Activity and its Relationship to Cardiovascular Risk Factors in Rural Japanese Men
- Pathologic Characteristics of Stroke and Myocardial Infarction in Japan:Akita Pathology Study
- Long-Term Prognosis after Stroke: A Community-Based Study in Japan.
- STUDIES ON EXPERIMENTAL SHOCK AND ITS PREVENTION IN GUIVEA PIGS BEING APPLIED STIMULATION TO THE PALATE
- Trends in the Incidence of Cardiovascular Diseases and their Risk Factors in a Rural Japanese Population
- ON THE PHARMACOLOGICAL ACTION OF 16-ACETYL DIGITALINUM VERUM