2. Polyps of the Colon and Rectum: Some Aspects in Patients with Frank Colorectal Carcinoma

概要

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346 polypoid lesions of the colon and rectum in 174 patients were histologically analysed in either biopsy or surgical specimens at the Aichi Cancer Hospital during the period 1965 to 1973. Polyosis and pseudopolyps in ulcerative colitis were excluded from this study.<BR>There were 108 men and 66 women. Of these, 73 patients had a frank colorectal carcinoma of which the highest incidence was noted in the seventh decade of life. The age peak in 101 patients without frank colorectal carcinoma was noted in the fifth decade of life and in 44 patients with adenoma alone was noted in the fifth decade of life. The vast majority of adenomas and malignant polyps were found in the sigmoid colon and the rectum. In patients with frank colorectal carcinoma coexistent adenomas and malignant polyps were similarly distributed in the colon and rectum. The incidence of malignant polyps was 19 percent in 205 polyps of 73 patients with frank colorectal carcinoma while being 13.4 per cent in 141 polyps of 101 patients unassociated with frank colorectal carcinoma. In general, malignant polyps were more to be pedunculated than sessile.<BR>It is conceivable from this study that there is a probable relationship among adenoma, malignant polyp and carcinoma of the colon and rectum.
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