Ovarian and Hepatic Metastases of Gastric Carcinoma Associated with High Serum Levels of Human Chorionic Gonadotropin (hCG), Alpha-Fetoprotein (AFP), and Carcinoembryonic Antigen (CEA): A Case Report.
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概要
- 論文の詳細を見る
A 45-year-old woman who underwent gastrectomy for gastric carcinoma which had metastasized to the liver and ovaries, showed high serum levels of hCG, AFP and CEA. To locate the source, an immunohistochemical technique was utilized. HCG-producing cells were detected in poorly differentiated adenocarcinoma of a primary tumor and an ovarian metastatic site, and AFP-producing cells in poorly differentiated adenocarcinoma forming a medullarypattern of primary site and metastatic foci. CEA-producing cells were found diffused in primary tumor and metastatic foci. From the viewpoint of oncodevelopmental gene expression (Cancer Res 36 : 3423, 1976), it is interesting that the serum levels of these three tumor markers (hCG, AFP, CEA) were elevated simultaneously.(Internal Medicine 31 : 260-264, 1992)
- 社団法人 日本内科学会の論文
著者
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Yamada Haruo
Department Of Applied Chemistry Graduate School Of Science And Engineering Tokyo Institute Of Techno
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Aoki Masahiro
Department of Cell Biology, National Institute for Basic Biology
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Hano Hiroshi
Department Of Diagnostic Pathology Hokkaido University Hospital
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Shimoda Tadakazu
Department Of Endoscopy Hiroshima University Hospital
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INAMOTO Yukio
Departments of Internal Medicine, Fuji Central Hospital
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HANO Hiroshi
Departments of Pathology, Fuji Central Hospital
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SANO Masataka
Departments of Internal Medicine, Fuji Central Hospital
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NAGAMINE NAGAMINE
Departments of Internal Medicine, Fuji Central Hospital
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OGIWARA Masao
Departments of Internal Medicine, Fuji Central Hospital
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SEKINO Shoichi
Departments of Obstetrics and Gynecology, Fuji Central Hospital
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HIRAMA Yoshiaki
Departments of Obstetrics and Gynecology, Fuji Central Hospital
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KAWAMURA Muneo
Kawamura Hospital
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AOKI Masahiro
Departments of Obstetrics and Gynecology, Fuji Central Hospital
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SHIMODA Tadakazu
Department of Pathology, The Jikei University School of Medicine
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YAMADA Haruo
Departments of Internal Medicine, Fuji Central Hospital
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