Borna Disease Virus Infection in Domestic Cats: Evaluation by RNA and Antibody Detection.

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概要

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• Borna disease virus (BDV) infection has been suggested to cause spontaneous neurological disease in cats referred to as staggering disease. However the evaluation of BDV infection in neurologically asymptomatic cats remained unclear. In the present study, BDV infected, asymptomatic cats in Tokyo were surveyed both by the presence of plasma antibodies against BDV-p24 and -p40 and by RNA detection in peripheral blood mononuclear cells. Seven of 32 domestic cats (21.9%) were serologically or genetically judged to be BDV-infected. Six cats were positive for anti-BDV antibody and two cats were positive for BDV RNA. Within the 2 RNA-positive cats, only one was positive for anti-BDV antibodies. Furthermore, the findings of anti-BDV-p40 and anti-BDV-p24 antibody-positive cats did not completely overlap. These results suggest that there are neurologically asymptomatic domestic cats infected with BDV present in the Tokyo area.

• 公益社団法人 日本獣医学会の論文

著者

• Nishino Yoshii

  Research Institute Of Biosciences School Of Veterinary Medicine Azabu University

• Funaba Masayuki

  Department Of Nutrition School Of Veterinary Medicine Azabu University

• Mizutani Tetsuya

  Laboratories Of Public Health Hokkaido University

• Hara Motonobu

  Department Of Microbiology Ii School Of Veterinary Medicine Azabu University

• NISHINO Yoshii

  Research Institute of Biosciences, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan

• IIZUKA Reiko

  Hirami Animal Hospital, 10-23 Tateno-cho, Nerima-Ku, Tokyo 177-0054, Japan

• HARA Motonobu

  Departments of Veterinary Microbiology II, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan

• FUNABA Masayuki

  Departments of Nutrition, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan

• FUKUSHIMA Ryoko

  Research Institute of Biosciences, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan

• KIMURA Takashi

  Comparative Pathology, Department of Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita-18, Nishi-9, Kita-Ku, Sapporo 060-0818, Japan

• HIRAMI Hiroshi

  Hirami Animal Hospital, 10-23 Tateno-cho, Nerima-Ku, Tokyo 177-0054, Japan

関連論文

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• Borna Disease Virus Infection in Domestic Cats: Evaluation by RNA and Antibody Detection.

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