Age-Dependent Changes in the Kidney Morphology of Female DBA/2 Mice
スポンサーリンク
概要
- 論文の詳細を見る
A female DBA/2 mouse is characterized by the presence of abundant cytoplasmic granules in the renal tubules. In the present study, the morphometrics of kidneys from female DBA/2 mice at 5, 15, 18, 21, and 24 months of age were investigated to determine the age-dependent renal changes in this mouse strain. Glomerular and tubulointerstitial disease progressed with age, and the semiquantitative scores of these lesions showed significant increases. Granules were observed in the proximal straight tubules and no changes were observed in their localization, fine structure, and quantitative scores. It was concluded that the tubular cytoplasmic granules in the female DBA/2 mouse were not affected by age-dependent functional reduction of the kidney.
著者
-
YABUKI Akira
Laboratory of Clinical Pathology, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University
-
YAMATO Osamu
Laboratory of Clinical Pathology, Department of Veterinary Clinical Sciences, Faculty of Agriculture, Kagoshima University
-
YAMATO Osamu
Laboratory of Clinical Pathology, Department of Veterinary Sciences, Kagoshima University
-
SUZUKI Shusaku
Shin Nippon Biomedical Laboratories Ltd.
関連論文
- Skin Morphology of the Clawn Miniature Pig
- Neuronal Nitric Oxide Synthase and Cyclooxygenase-2 in Diabetic Nephropathy of Type 2 Diabetic OLETF Rats
- Retrospective Diagnosis of Feline GM2 Gangliosidosis Variant 0 (Sandhoff-Like Disease) in Japan: Possible Spread of the Mutant Allele in the Japanese Domestic Cat Population
- Identification of heat shock protein 70 in canine reticulocytes and mature erythrocytes
- Relation between Reticulocyte Count and Characteristics of Erythrocyte 5'-Nucleotidase in Dogs, Cats, Cattle and Humans
- Age-Dependent Changes in the Kidney Morphology of Female DBA/2 Mice
- Morphological Analysis of Corneal Opacity in Shiba Dog with GM1 Gangliosidosis(Anatomy)
- Isolation and Identification of Sodium 2-Propenyl Thiosulfate from Boiled Garlic (Allium sativum) That Oxidizes Canine Erythrocytes(Organic Chemistry)
- Fine Structure of the Parotid and Mandibular Glands of the Cotton Rat (Sigmodon hispidus)
- SAMP1/Sku as a Murine Model for Tubulointerstitial Nephritis : a Study Using Unilateral Ureteral Obstruction
- Neuronal Ceroid-lipofuscinosis in a Japanese Domestic Shorthair Cat
- Bacillary Hemoglobinuria in Japanese Black Cattle in Hiroshima, Japan: A Case Study
- Rodent Renal Structure Differs among Species
- Successful Treatment of Bacillary Hemoglobinuria in Japanese Black Cows
- Different A-Type Natriuretic Peptide Level in Five Strains of Mice
- Pathological Features of Salivary Gland Cysts in a Shiba Dog with GM1 Gangliosidosis: A Possible Misdiagnosis as Malignancy
- Clinical and Clinico-Pathologic Characteristics of Shiba Dogs with a Deficiency of Lysosomal Acid β-Galactosidase: A Canine Model of Human GM1 Gangliosidosis
- アンギオテンシン？タイプ1a受容体遺伝子欠損マウスにおける心房性ナトリウム利尿ペプチド動態
- Trapped Neutrophil Syndrome in a Border Collie Dog: Clinical, Clinico-Pathologic, and Molecular Findings
- Rapid-Air-Dry Papanicolaou Stain in Canine and Feline Tumor Cytology: A Quantitative Comparison with the Giemsa Stain
- Identification of Bangladeshi Domestic Cats with GM1 Gangliosidosis Caused by the c.1448G>C Mutation of the Feline GLB1 Gene: Case Study
- Association between the Intrarenal Renin-Angiotensin System and Renal Injury in Chronic Kidney Disease of Dogs and Cats
- Genotyping Assays for the Canine Degenerative Myelopathy-Associated c.118G>A (p.E40K) Mutation of the SOD1 Gene Using Conventional and Real-Time PCR Methods: A High Prevalence in the Pembroke Welsh Corgi Breed in Japan
- Species Specific Differences in the Ratio of Short to Long Loop Nephrons in the Kidneys of Laboratory Rodents
- Real-Time PCR Genotyping Assay for GM2 Gangliosidosis Variant 0 in Toy Poodles and the Mutant Allele Frequency in Japan
- Preventive Effect of Mildly Altering Dietary Cation-Anion Difference on Milk Fever in Dairy Cows