Different A-Type Natriuretic Peptide Level in Five Strains of Mice
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概要
- 論文の詳細を見る
Atrial (A-type) natriuretic peptide (ANP) is vasodilator hormone involved in the regulation of blood pressure and volume homeostasis. In this study, we examined the differences of the auricular and plasma ANP distribution by immunohistochemistry, ultrastructural morphometry, and radioimmunoassay in five strains of mice. The ANP-immunoreactivities of the auricle were most intense in ICR, and moderate in C57BL/6J and C3H/HeN, and weakest in BALB/cA and DBA/2Cr. The number of ANP-granules was greatest in ICR followed by C57BL, C3H or BALB/c, and DBA/2 mice, in this order. The auricular ANP content was highest in ICR, but the plasma ANP concentration was comparable in all strains. The present study demonstrates that there are differences in the ANP circulating system between five strains.
著者
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Mifune Hiroharu
Institute Of Animal Experiment Kurume University School Of Medicine
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Yabuki Akira
Laboratory Of Veterinary Anatomy Department Of Veterinary Medicine Faculty Of Agriculture Kagoshima
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Tajiri Yuji
Division Of Endocrinology And Metabolism Department Of Medicine Kurume University School Of Medicine
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Nishi Yoshihiro
Department Of Physiology Kurume University School Of Medicine
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MIFUNE Hiroharu
Institute of Animal Experimentation, Kurume University School of Medicine, Fukuoka 830-0011, Japan
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YABUKI Akira
Laboratory of Veterinary Clinical Pathology, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, Kagoshima 890-0065, Japan
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YABUKI Akira
Laboratory of Clinical Pathology, Department of Veterinary Medicine, Kagoshima University
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TAJIRI Yuji
Division of Endocrinology and Metabolism, Kurume University School of Medicine, Fukuoka 830-0011, Japan
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YABUKI Akira
Laboratory of Clinical Pathology, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University
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NISHI Yoshihiro
Department of Physiology, Kurume University School of Medicine, Fukuoka 830-0011, Japan
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