Inhibitory Effects of Bakuchiol, Bavachin, and Isobavachalcone Isolated from Piper longum on Melanin Production in B16 Mouse Melanoma Cells
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概要
- 論文の詳細を見る
An EtOH extract of fruits of Piper longum was found to exhibit a potent inhibitory effect against α-melanocyte-stimulating hormone (α-MSH)-induced melanin production in B16 mouse melanoma cells. Bioassay-directed fractionation led to the isolation of prenylated phenolic compounds bakuchiol, bavachin, and isobavachalcone. These compounds and the crude extract of the fruits of P. longum may have suppressive effects against pigmentation by melanin in the skin.
著者
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Ohno Osamu
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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Watabe Taeko
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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Nakamura Kazuhiko
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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KAWAGOSHI Masaru
FANCL Research Institute, FANCL Corporation
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UOTSU Nobuo
FANCL Research Institute, FANCL Corporation
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CHIBA Tomohiro
FANCL Research Institute, FANCL Corporation
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YAMADA Masayoshi
FANCL Research Institute, FANCL Corporation
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YAMAGUCHI Kohji
FANCL Research Institute, FANCL Corporation
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YAMADA Kaoru
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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MIYAMOTO Kenji
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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UEMURA Daisuke
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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