Point mutations in domain II of the voltage-gated sodium channel gene in deltamethrin-resistant Aedes aegypti (Diptera: Culicidae)
スポンサーリンク
概要
- 論文の詳細を見る
The continuous usage of pyrethroids against insects has provoked the emergence of insecticide resistance that has become a major obstacle to disease vector control. The knockdown resistance (kdr) voltage-gated sodium channel gene is regarded as a key to understanding the mechanism of resistance to pyrethroids. The main purpose of this study is to identify point mutations in the sodium channel gene associated with deltamethrin resistance in Aedes aegypti. Two mutations in the IIS6 domain of the channel, S989P and V1016G, were identified as possible candidates responsible for the emergence of deltamethrin resistance in Ae. aegypti Khu Bua strain. As S989P and V1016G mutations are located within the IIS5–S6 loop and IIS6 near the ion filter and binding site, these mutations might enhance pyrethroid resistance. Allelic variation in the sodium channel gene is thought to be one of the principal molecular mechanisms regulating pyrethroid resistance in mosquitoes.
- Japanese Society of Applied Entomology and Zoologyの論文
著者
-
Srisawat Raweewan
Department of Medical Entomology Faculty of Medicine, Mahidol University
-
KOMALAMISRA Narumon
Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University
-
MATSUMOTO Akira
Department of Microbiology, Kawasaki Medical School
-
Ono Katsushige
Department of Cardiovascular Science, Oita University School of Medicine
-
Zheng Mingqi
Department of Cardiovascular Sciences, Oita University School of Medicine
-
ESHITA Yuki
Department of Parasitology, Kurume University School of Medicine
-
Ono Katsushige
Department Of Cardiovascular Science Faculty Of Medical Oita University
-
Eshita Yuki
Department Of Infectious Diseases Faculty Of Medicine Oita University
-
Zheng Mingqi
Department Of Cardiovascular Sciences Oita University School Of Medicine
-
Itoh Taichi
Graduate School of Systems Life Sciences, Kyushu University
-
Petmitr Songsak
Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University
-
Rongsriyam Yupha
Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University
-
Petmitr Songsak
Department Of Tropical Nutrition And Food Science Faculty Of Tropical Medicine Mahidol University
-
Matsumoto Akira
Department Of Aeronautics And Astronautics Faculty Of Engineering Kyushu University
-
Srisawat Raweewan
Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University
-
Eshita Yuki
Department of Infectious Disease Control, Faculty of Medicine, Oita University
-
Zheng Mingqi
Department of Cardiovascular Science, Faculty of Medicine, Oita University
-
Ono Katsushige
Department of Cardiovascular Science, Faculty of Medicine, Oita University
関連論文
- A01 蚊類のアルボウイルス媒介能 (11) : 北海道産ヤマトヤブカのウエストナイルウイルス感受性(第59回日本衛生動物学会大会特集)
- デングウイルスを媒介可能なヒトスジシマカの卵の孵化に与える,餌,卵密度および同種未成熟幼虫の効果
- Continuous Isolation and Characterization of Chlamydia pneumoniae from a Patient with Diffuse Panbronchiolitis
- Beneficial Effects of the Dual L- and T-Type Ca^ Channel Blocker Efonidipine on Cardiomyopathic Hamsters
- Denervation and Reinnervation of the Heart After Aortic Surgery, Estimated by ^I-Metaiodobenzylguanidine Scintigraphy
- OE-135 Transcription Factors Csx/Nkx2.5 and GATA4 Distinctly Regulate Expression of Ca^ Channels in Neonatal Rat Heart(Development and differentiation-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Mitogen-Activated Protein Kinase (MAPK) p38 Pathway Modulates P19CL6-Derived Cardiomyocytes Differentiation via the Activation of Cardiac Specific Transcription Factor GATA4(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circu
- タイ国諸分布地域のコガタハマダラカ種群のアイソザイムの遺伝的変異
- Effects of Antiarrhythmic Drugs on Apoptotic Pathways in H9c2 Cardiac Cells
- The Application of Molecular Biological Tools to Epidemiology of African Trypanosomosis
- Pheochromocytoma Presenting as Recurrent Hypotension and Syncope
- Different role of angiotensin II type 1 and type 2 receptors in renin release by interaction of angiotensin II and renal sympathetic nerve
- Modulation of Angiotensin II Type 1 Receptor mRNA Expression in Human Blood Cells: Comparison of Platelets and Mononuclear Leucocytes
- Predominant methyl radical initiation preceded by β-scission of alkoxy radicals in allyl polymerization with organic peroxide initiators at elevated temperatures
- PE-024 Combination of Cilostazol and Bepridil, a Potential Anti-Fibrillation Medication in Patients with Idiopathic Ventricular Fibrillation(Arrhythmia, therapy(11)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation
- PJ-198 Ethanol-induced Tachycardia is Mediated by T-type Ca^ Channel Regulation Caused by Transcription Factor Csx/Nkx2.5 Activation(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
- The 7.5-kb common plasmid is unrelated to the drug susceptiility of Chlamydia trachomatis
- A07 Ecological and physiological determinants of the midgut proteome of the dengue vector Aedes albopictus (Diptera: Culicidae)
- Effects of Differential Hypothermia on Adenovirus Type 12 Induced Cheek Pouch Tumors : Histochemical Study of Hydrolytic and Glycolytic Enzymes
- In Vitro Susceptibility of 7.5-kb Common Plasmid-Free Chlamydia trachomatis Strains
- Effect of photoperiod on blood feeding activity of female hybrids between Culex pipiens pipiens and Culex pipiens quinquefasciatus (Diptera: Culicidae)
- A Case of Crush Syndrome With Giant Negative T Waves and Reversible Left Ventricular Dysfunction
- Attenuated Listeria infection activates natural killer cell cytotoxicity to regress melanoma growth in vivo
- Differential Effect of Listeria monocytogenes Infection on Cytokine Production and Cytotoxicity of CD8 T Cells
- Primary Ileal Volvulus Neonates:Radiologic Findings in Two Cases
- Achalasia Complicated by Multiple Intramucosal Carcinomas : Report of a Case
- LOCALIZATION OF SUDANOPHIL MATERIAL AT THE SITES OF CALCIFICATION IN DENTINE. AND THE COMPACT BONE AND EPIPHYSEAL CARTILAGE PLATE OF TIBIA IN THE RAT GIVEN BERYLLIUM CARBONATE
- 38. Clinical and Neurophysiological Investigation of the Preventive Effect to Convulsive Seizure by Means of Administration of GABA(γ-aminobutylic acid) Derivatives to CSF Cavity
- Reassessment of Free-Radical Polymerization Mechanism of Allyl Acetate Based on End-Group Determination of Resulting Oligomers by MALDI-TOF-MS Spectrometry
- Developmental Profiles of Phosphorylated and Unphosphorylated CREBs in Murine Calvarial MC3T3-E1 Cells
- Quantitative Analysis of Alkaline Phosphtase Activity and Mineralization of a Clonal Osteoblast-like Cell MC3T3-E1
- The Gating and Conductance Properties of Ca_v3.2 Low-Voltage-Activated T-Type Calcium Channels
- Roles of α_1 and α_1/β Subunits Derived from Cardiac L-Type Ca^ Channels on Voltage-Dependent Facilitation Mechanisms
- Pharmacological properties of the human cardiac cloned T-type calcium channel
- SEROEPIDEMIOLOGY OF DENGUE AND ASSESSMENT OF PUBLIC AWARENESS IN THE DOMINICAN REPUBLIC
- Laparoscopic Heller Myotomy and Dor Fundoplication Combined with Laparoscopic Diverticular Introversion Suturing for Achalasia Complicated by Epiphrenic Diverticulum : Report of a Case
- The changes of c-fos mRNA expression in the osteoblastic MC3T3-E1 cells with the treatment of EGF and TPA under a low-calcium environment
- Ca^ Influx through the Remodeled T-Type Ca^ Channel for Contraction in Hypertrophied Ventricles in Rats
- Ischemic preconditioning was mediated by protein kinase C but not phosphatidylinositol-3'-kinase in guinea-pig hearts
- cDNA CLONING OF CLOCK GENES IN TWO SPECIES OF CRICKETS GRYLLUS BIMACULATUS AND MODICOGRYLLUS SIAMENSIS(Physiology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- Outcomes of Radiotherapy for Inoperable Locally Advanced (T4) Esophageal Cancer - Retrospective Analysis -
- Hormonal Alteration of Synaptic Input to Mauthner Cells of the Adult Male Red-Bellied Newts
- Treatment Results of Chemoradiation for T1 Esophageal Cancer with Lymph Node Metastases
- 29. High-intensity voluntary exercise regulates cardiac autonomic nerve activity in SPORTS rats(The Proceedings of the 15th Annual Meetings of Japan Society of Exercise and Sports Physiology July 26-27, (Hirosaki))
- PJ-599 Contribution of T-type Ca^ Channels to Apoptosis(Arrhythmia, basic-5 (A) PJ101,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Inhomogeneous Derangement of Cardiac Autonomic Nerve Control in Diabetic Rats
- Detection of acute cardiac rejection by analysis of heart rate variability in heterotopically transplanted rats
- Rescue of Pulmonary Hypertension with an Oral Sulfonamide Antibiotic Sulfisoxazole by Endothelin Receptor Antagonistic Actions
- -180-INHIBITORY EFFECTS OF MEXILETINE AND LIDOCAINE ON THE CALCIUM CURRENT OF SINGLE VENTRICULAR MYOCYTES
- PJ-565 Amiodarone Either Prevents or Synergistically Promotes H_2O_2-induced Apoptosis of HL-1 Cardiac Cells Depending on Its Concentration(Cardiovascular pharmacology, basic/clinical-6, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
- Ultrastructure and Cytoarchitecture of Bachmann's Bundle in the Mammalian Heart
- Syntheses and Properties of π-Conjugated Polymers Containing Chromophore.2.Introduction of Porphyrin Units into Main Chain of Water-Soluble Small Band Gap Polymer
- Syntheses and Properties of π-Conjugated Polymers Containing Chromophore. 1. Water-Soluble Small-Bandgap Polymer Backbone
- Electron Spin Resonance Spectroscopic Pursuit of Network Formation Processes in Free-Radical Crosslinking Polymerizations I. Microscopic Environmental Evaluation around Copper(II) Tetraphenylporphyrin Spin Probe Incorporated into or Excluded from Polymer
- Synthesis of Novel π-Conjugated Polymer Containing Porphyrins
- Specific Polymerization Behavior of Triallyl Isocyanurate. Accumulation of Radicals before Gelation
- Foreward : Molecular epidemiology of viral infection in Asia
- Molecular Basis for Adaptation of a Chimeric Dengue Type-4/Japanese Encephalitis Virus to Vero Cells
- Point mutations in domain II of the voltage-gated sodium channel gene in deltamethrin-resistant Aedes aegypti (Diptera: Culicidae)
- Identification of the Carboxyl-Terminal Processing Protease for the D1 Precursor Protein of the Photosystem II Reaction Center of Spinach : PROTEINS, ENZYMES AND METABOLISM : MEMBRANES AND BIOENERGETICS
- SiO_2を Sputtering したNi-20Cr-1Si合金の高温耐酸化性
- Suppressed localization of a major autolysin on Staphylococcus aureus treated with tetracycline
- Subcellular Localization of the Major Autolysin, ATL and Its Processed Proteins in Staphylococcus aureus
- Effect of Organic Buffer Layer on Performance of Pentacene Field-Effect Transistor Fabricated on Natural Mica Gate Dielectric
- Nonapeptide Hormones Oxytocin and Vasopressin Distinctly Regulate Ca_v1.2 L-type Calcium Channel Expression in Cardiomyocytes
- Merging Beams Apparatus for Studying Ion-neutral Reactions.
- Further Duscussion of the Specific Polymerization Behavior of Triallyl Isocyanurate. Enhanced Occurrence of Intermolecular Crosslinking at an Early Stage of Polymerization
- 2. Ambient Cistern as a Intracerebral Reference Point for Thalamotomy
- Microbiology of Chlamydiae : with Emphasis on Physiocochemistry, Antigenicity and Drug Susceptibility of Chlamydia pneumoniae
- Tyrosine phosphatase-like activity of bone-type alkaline phosphatase at neutral pH range
- Analysis of sequence variation in Gnathostoma spinigerum mitochondrial DNA by single-strand conformation polymorphism analysis and DNA sequence
- 1P-Y-18 Effects of voluntary exercise on calcium ion channel expression and contraction of the heart in SPORTS rats(The Proceedings of the 16th Annual Meetings of Japan Society of Exercise and Sports Physiology August 2-3, (Nara))
- A-4. Attempts of Measuring the Increment Rate of Water Contents in Edematous Brain Tissues by ^3H_2O-Liquid Scintillation Counter
- S-II-8. The Changes of CSF Dynamics and Normal Pressure Hydrocephalus Following Subarachnoid Hemorrhage
- Fabrication of an Organic Field-effect Transistor on a Mica Gate Dielectric
- A Study on High Temperature Effects in Shock Wave/Boundary Layer Interaction Induced by Compression Corner
- Immunohistochemical Analysis of Androgen Receptor in the Abdominal Glands of the Cloaca of Male Red-Bellied Newts, Cynops pyrrhogaster
- Effects of X-Ray Irradiation on the Subsequent Gonadotropin Secretion in Normal and Neonatally Estrogenized Female Rats
- Distribution of a Human Brain Carboxypeptidase B Capable of Cleaving β-Amyloid Precursor Protein(APP) in Normal and Alzheimer's Diseased Brain
- Expression of human brain carboxypeptidase B, a possible cleaving enzyme for β-amyloid precursor protein, in peripheral fluids
- Control of Biological Activities of Influenza Virus Hemagglutinin by Its Carbohydrate Moiety
- Band Gap and Absorption Profile Change by Changing Molecular Weight and Conformation of Water-soluble Narrow-band-gap Polymers
- Copolymerization of Poly(allyl methacrylate) Crosslinked Polymer Microspheres with Allyl Benzoate
- Degradation of Ultrahigh Molecular Weight Poly(styrene-co-m-divinylbenzene)s as Network-Polymer Precursors in SEC Columns
- Further Discussion of Correlation between Brittleness and Network Structure of Triallyl Isocyanurate Resins
- The Vomeronasal System and Its Connections with Sexually Dimorphic Neural Structures
- Emulsion Crosslinking Polymerization of Vinyl Methacrylate as Compared with Allyl Methacrylate
- Continuous Band Gap Control from 0.3 to 1.1eV of π-Conjugated Polymers in Aqueous Solution
- Microgel-like network polymer precursor formation in free-radical cross-linking multiallyl polymerization
- Neural and Hormonal Control of Lordosis Behavior in the Rat
- ION ENERGY LOSS SPECTRA OF N_2 AND CO
- Sex Difference in Volume of the Ventromedial Nucleus of the Hypothalamus in the Rat
- Approach to Ideal Network Formation in Free-Radical Crosslinking Copolymerization of Benzyl Acrylate with 1,6-Hexanediol Diacrylate
- Detection and isolation of nanobacteria-like particles from urinary stones : Long-withheld data
- Prevalence of pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae among heterosexual men in Japan
- Study of Negative Ion Formations by Electron Impact I. Negative Ions Produced from Acrylonitrile
- Dengue virus type 2 recognizes the carbohydrate moiety of neutral glycosphingolipids in mammalian and mosquito cells
- Ion-Molecule Reactions in Acetaldehyde and Methanol
- Theoretical Treatment of Unimolecular Dissociation Reaction of Diatomic Metastable Ions
- Effects of Antiarrhythmic Drugs on Apoptotic Pathways in H9c2 Cardiac Cells