Leydig Cell Tumor and Malignant Lymphoma in a Patient with Nonclassical 21-Hydroxylase Deficiency
スポンサーリンク
概要
- 論文の詳細を見る
A 46-year-old man was admitted in our hospital with hypoglycemia; his FPG was 43 mg/mL. Five years earlier, he underwent simultaneous surgeries for an adrenal adenoma, a benign Leydig cell tumor (LCT), and a malignant lymphoma. Based on the laboratory results, he was diagnosed as congenital adrenal hyperplasia (CAH) due to nonclassical 21-hydroxylase deficiency (21-OHD). On immunohistochemistry analysis using the antibody against adrenal-specific 11β-hydroxylase antibody, the LCT showed both properties as a testicular cell and as an adrenal cell. The genetic background of 21-OHD might contribute to the development of malignant lymphoma. Such as a case of LCT and malignant lymphoma in a patient with 21-OHD seems to be rare.
著者
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Suzuki Satoru
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine
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Inaba Hidefumi
Department Of Aging Medicine And Geriatrics Shinshu University Graduate School Of Medicine
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Uehara Takeshi
Department Of Central Laboratory Shinshu University School Of Medicine
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OHFUSA HIROKAZU
Nagano Red Cross Hospital
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Hashizume Kiyoshi
Department Of Aging Medicine And Geriatrics Institute On Aging And Adaptation Shinshu University Gra
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Shigematsu Satoshi
Department of Aging and Geriatrics, Shinshu University, Graduate School of Medicine
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Shinomiya Ken
Department of Aging and Geriatrics, Shinshu University, Graduate School of Medicine
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Shimojo Yasuyo
Department of Laboratory Medicine, Shinshu University School of Medicine
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Hashizume Kiyoshi
Department of Aging and Geriatrics, Shinshu University, Graduate School of Medicine
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Suzuki Satoru
Department of Aging and Geriatrics, Shinshu University, Graduate School of Medicine
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Inaba Hidefumi
Department of Aging and Geriatrics, Shinshu University, Graduate School of Medicine
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