Transient Polyuria Related to Central Diabetes Insipidus Caused by Lymphocytic Infundibulo-neurohypophysitis in a Patient Treated for Graves Disease
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概要
- 論文の詳細を見る
A 45-year-old man was hospitalized because of weight loss, finger tremor, thirst, polydipsia and increased urinary frequency. He was diagnosed with Graves disease (GD) and central diabetes insipidus (CDI). Magnetic resonance imaging revealed the enlarged posterior pituitary with thickened stalk. Histological examination obtained from biopsy of the pituitary revealed lymphocytic infundibulo-neurohypophysitis. He received treatment with thiamazole (MMI) for GD and desmopressin acetate (DDAVP) for CDI. However, DDAVP administration could be discontinued as GD was gradually improved. This course indicates that not only the recovered renal response to arginine-vasopressin but also the immunomodulative effects of MMI might attribute to the improvement of polyuria.
著者
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Nishio Shin-ichi
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine
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Yamazaki Masanori
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Sato Ai
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Uehara Takeshi
Department of Laboratory Medicine, Shinshu University School of Medicine
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Komatsu Mitsuhisa
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Nishio Shin-ichi
Department Of Aging Medicine And Geriatrics Shinshu University
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Yamazaki Masanori
Department Of Aging Medicine And Geriatrics Institute On Aging And Adaptation Shinshu University Gra
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Komatsu Mitsuhisa
Department Of Aging Medicine And Geriatrics Graduate School Of Medicine Shinshu University
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Uehara Takeshi
Department Of Central Laboratory Shinshu University School Of Medicine
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Yamazaki Masanori
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation, Shinshu University Graduate School
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