Distinct Clinical Courses in Type 1 Diabetes Mellitus Induced by Peg-interferon-α Treatment for Chronic Hepatitis C
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概要
- 論文の詳細を見る
We report two cases of type 1 diabetes mellitus (T1DM) which developed after interferon (IFN) therapy for chronic hepatitis C. The patients had experienced abrupt hyperglycemia with positive anti-glutamic acid decarboxylase antibodies, resulting in initiation of insulin therapy. In one case, insulin therapy could be discontinued because endogenous insulin secretion was preserved at the onset and pancreatic β cell function was recovered thereafter. In the other case with Hashimotos thyroiditis and Sjögrens syndrome, continuation of insulin therapy was necessary because blood glucose levels were unstably controlled. Lasting autoimmunity superior to immunosuppressive mechanism may be associated with distinct clinical courses in these cases.
著者
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Yamazaki Masanori
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Sato Ai
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Komatsu Mitsuhisa
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Takeda Teiji
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation
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Yamazaki Masanori
Department Of Aging Medicine And Geriatrics Institute On Aging And Adaptation Shinshu University Gra
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Komatsu Mitsuhisa
Department Of Aging Medicine And Geriatrics Graduate School Of Medicine Shinshu University
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Takeda Teiji
Department Of Aging Medicine And Geriatrics Institute On Aging And Adaptation Shinshu University Gra
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Yamazaki Masanori
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation, Shinshu University Graduate School
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Takeda Teiji
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation, Shinshu University Graduate School
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Sato Ai
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation, Shinshu University Graduate School
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Komatsu Mitsuhisa
Department of Aging Medicine and Geriatrics, Division of Medicine, Institute on Aging and Adaptation, Shinshu University Graduate School
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