Health-related Quality of Life in Patients with Idiopathic Pulmonary Fibrosis -Cross-sectional and Longitudinal Study-
スポンサーリンク
概要
- 論文の詳細を見る
Object To validate the cross-sectional and longitudinal use of the Medical Outcome Study Short Form 36 (SF-36) for measuring health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF). Methods Patients were administered the SF-36 and concomitantly underwent laboratory and physiologic tests and high-resolution computed tomography (HRCT). Forty-six patients participated in the initial cross-sectional study, and 32 patients who were available more than one year later again underwent these studies under the same conditions. Results Patients with IPF had significantly lower scores across all 8 domains of the SF-36 when compared with the general population. Significant decline of HRQL was observed in 2 physical domains. There were significant differences in within-subject changes in a few domains according to worsening of the physiologic parameters. Vital capacity as percent of predicted was significantly correlated with the results of 6 subscales and its changes were significantly correlated with those of 4 subscales. The 6-min-walk distance was correlated significantly with 3 subscales and its changes were significantly correlated with those of 4 subscales. Changes in the HRCT ground-glass score were significantly correlated with those of 3 subscales. No significant correlations between changes in 3 domains and those of any clinical parameters were observed. Conclusion Patients with IPF had significantly impaired HRQL in both physical and psychological functions. This disease clearly decreased the physical aspects of HRQL over time. HRQL instruments should be incorporated into routine evaluations of IPF patients, since they measure dimensions not fully estimated by clinical assessment.
著者
-
Hashimoto Kimio
Department Of Electrical Engineering Faculty Of Engineering Kyushu University
-
Imanaka Kazufumi
Department Of Radiology Nishi-kobe Medical Center
-
Iwasaki Hironobu
Department Of Respiratory Medicine Nishi-kobe Medical Center
-
Tomioka Hiromi
Department of Respiratory Medicine, Kobe City Medical Center West Hospital, Japan
-
Tomioka Hiromi
Department of Respiratory Medicine, Nishi-Kobe Medical Center
関連論文
- Aortico-pulmonary Paraganglioma : Case Report and Japanese Review
- Application of Self-expanding Metallic Stents to Malignant Stricture following mechanically Stapled Esophagojejunostomy:Report of Two Cases
- Fusion of intussusceptum and intussuscipiens in intrauterine intussusception : A rare type of intestinal atresia
- In-Diffusion and Annealing of Copper in Germanium
- Numerical Solutions of Basic Equations for Kick-Out Mechanism of Diffusion
- Diffusion Mechanism of Nickel and Point Defects in Silicon
- Criterions for Basic Assumptions in Kick-Out Mechanism of Diffusion
- Solid Solubility of Cobalt in Silicon
- Primary large cell neuroendocrine carcinoma of the urinary bladder
- Galvanomagnetic Effects in Bismuth Selenide Bi_2Se_3
- Electrical Properties of TlSe
- Diffusion Coefficient of Iron in Silicon at Room Temperature
- Developmental Abnormalities of Dendrites of the Cerebral Cortical Neurons in Mental Retardation
- Diffusion Coefficient of Cobalt in Silicon
- Energy Level and Solid Solubility of Cobalt in Silicon by In-Depth Profile Measurement
- Differential Method for Measuring Thermally Stimulated Capacitance
- Simple ICTS Measurement Method
- Note on the Analysis of DLTS and C^2-DLTS
- Magnetic resonance imaging findings of endometrioid adenocarcinoma of the ovary
- Ring Enhancement on T_1-weighted GRE Images after Ferucarbotran Administration for Hepatic Metastasis : Comparison with Pathological Findings : Case Report
- Diffusion of Electrically-Active Cobalt in Silicon
- Trap Levels of Beryllium in Silicon
- Method of Analysis of a Single-Peak DLTS spectrum with Two Overlapping Deep-Trap Responses
- Atypical carcinoid of thymus associated with multiple endocrine neoplasia syndrome type 1
- MRI Finding of Chronic Hemorrhagic Empyema : A Case Report
- Electrical Properties of Stannous Telluride SnTe
- Electrical Properties of SnTe, SnSe and InBi at Low Temperatures
- Reirradiation Therapy for Brain Metastases from Small Cell lung Cancer
- Annealing of Supersaturated Cobalt in Silicon
- A Survey of Patients with Inflammatory Skin Recurrence Corresponding to the Area of Previous Irradiation after Postoperative Radiotherapy for Breast Cancer
- Health-related Quality of Life in Patients with Idiopathic Pulmonary Fibrosis -Cross-sectional and Longitudinal Study-
- Deep Impurity Levels of Cobalt in Silicon
- Polarization of Electrons by Scattering, III Reflection-Transmission Effect
- Association of Hyperglycemia on Admission and During Hospitalization with Mortality in Diabetic Patients Admitted for Pneumonia