Dietary Isothiocyanates Modify Mitochondrial Functions through Their Electrophilic Reaction
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概要
- 論文の詳細を見る
We found that both benzyl isothiocyanate (ITC) and phenyl ITC inhibited respiration in the mitochondria in an electrophilic reaction-dependent manner. ITC-induced mitochondrial swelling and cytochrome c release were prevented by cyclosporin A, indicating that they are mediated through the ITC moiety-dependent reaction to critical thiol groups for the opening of membrane permeability transition-dependent pores.
- 社団法人 日本農芸化学会の論文
- 2005-12-23
著者
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Kawakami Makiko
Department of Emergency Medicine, Osaka Mishima Emergency and Critical Care Center
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NAKAMURA Yoshimasa
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University
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HARADA Nobuhiro
Department of Electrical Engineering, Nagaoka University of Technology
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Kawakami Makiko
Department Of Biochemistry School Of Medicine Fujita Health University
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Nakamura Yoshimasa
Dep. Of Biofunctional Chemistry Div. Of Bioscience Graduate School Of Natural Sci. And Technol. Okay
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Harada Nobuhiro
Department Of Biochemistry School Of Medicine Fujita Health University
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KAWAI Kiyoshi
Faculty of Home Economics, Chukyo Women's University
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Nakamura Yoshimasa
Department Of Biofunctional Chemistry Division Of Bioscience Graduate School Of Natural Science And
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Harada Nobuhiro
Department Of Biochemistry Fujita Health University
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HIRATSUKA Mio
Faculty of Wellness, Chukyo Women's University
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Hiratsuka Mio
Faculty Of Wellness Chukyo Women's University
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Kawai Kiyoshi
Faculty Of Wellness Chukyo Women's University
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Nakamura Yoshimasa
Department Of Applied Mathematics And Physics Faculty Of Engineering Kyoto University
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