[原著］Budd-Chiari症候群13例の臨床的、生化学的所見の検討

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It has been recently reported that primary Budd-Chiari syndrome (BC-S), obstruction of the hepatic portion of the inferior vena cava, can be cured by surgical treatment, while at the same time a relatively high occurrence rate of primary hepatocellular carcinoma in BC-S has also been reported. Hence, early detection of BC-S may lead to good prognosis. To elucidate clinical characteristics of BC-S, 13 consecutive patients with the disease were investigated. The diagnosis of the syndrome was made by ultrasound, and subsequently comfirmed by cavography. Their demographic and clinical data were compared with those of patients with liver cirrhosis associated with other etiology (alcohol consumption: 25 patients, hepatitis B and/or C virus infection: 85, cryptogenic: 15). The mean age at diagnosis of the 13 patients with BC-S was $45.3 \pm 9.5$, and significantly younger than both that of patients with virus related and cryptogenic liver cirrhosis. On admission.7 of the 13 showed normal value of transaminases, and 5 0f the remaining 6 showed a slight elevation. Mean values of transaminases (GOT and GPT) on admission of patients with BC-S were significantly lower than those of each of the 3 other subgroups. Serum albumin concentrations were normal in 8 of the 13 patients, whereas all but one (who showed a very high value of serum bilirubin) had a slightly elevated value of serum bilirubin (less than 3 g/dl) on admission. Clinical features suggestive of BC-S include relatively younger age, and normal or nearly normal liver biochemical tests except for indirect domimant hyperbihrubinemia.
琉球医学会,Ryukyu Medical Associationの論文

[原著］Budd-Chiari症候群13例の臨床的、生化学的所見の検討

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