Quantitative Evaluation of Left Ventricular Relaxation by Apexcardiogram in Coronary Artery Disease．
スポンサーリンク
概要
- 論文の詳細を見る
To assess non-invasively whether the location,extent and severity of left ventricular (LV) contraction abnoumalities affect LV relaxation, we studied apexcardiogram (ACG) in 48 patients with coronary artery disease (CAD) of over 75% luminar stenosis and 16 control subjects under basal conditions within a week before cardiac catheterization. Asynergy of LV wall motion was classified on the basis of AHA committee ventriculography reporting system. The patients consisted of control sudjects [Group I:n=16]and the patients with CAD of one-vessel disease in right coronary artery or left circumflex coronary artery stenosis[Group II ; n=16],of one-vessel disease in left anterior descending coronary artery stenosis [Group III ; n=20] and of three-vessel disease associated with general hypokinesis[Group IV ; n=12]. ⊿ｔ was defined as the time interval between the anortic compoment of the second heart sound heart sound (A2) and the 50% height of ACG deflection from the end-systolic shoulder of the onest of A2 to the nadir of ACG (O-point), during isovolumic relaxation period. ⊿ｔ was significantly prolonged in Group III (60±12 msec, P<0.05) and Group IV (73±12 msec, P<0.01) comparted to in group I (51±11 msec). There were good correlations between ⊿ｔ and LV peak negative dP/dt(r=-0.44, P<0.01) and between ⊿ｔ and time constant of isovolumic LV presure decay (r=0.54, P<0.01). ⊿ｔ reflects the impairment of LV relaxation, and then the extent and/or severity rather than the locality of LV wall motion abnormalities increased ⊿ｔ,probadly due to a global impairment of LV relaxation.
- Yamaguchi University Graduate School of Medicineの論文
著者
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Obayashi Masakazu
Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi Univesity Graduate
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Ozaki Masaharu
2nd. Dept. Of Internal Med. Yamaguchi Univ. Ube Yamaguchi Japan
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Kumada Toshiaki
The Third Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Kumada Toshiaki
The 3rd Medical Clinic Kyoto University Hospital
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Kumada Toshiaki
The 2nd Department Of Internal Medicine Faculty Of Medicine Yamaguchi University
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Kumada Toshiaki
The Division Of Internal Medicine Yamaguchi University School Of Medicine
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Kusukawa Reizo
Department Of Cardiology Tenri Hospilal
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Ozakl Masaharu
Department Of Internal Medicine Yamaguchi University School Of Medicine
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Obayashi Masakazu
Department Of Medical Bioregulation Division Of Cardiovascular Medicine Yamaguchi University School
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Obayashi Masakazu
Department Of Medical Bioregulation Division Of Cardiovascular Medicine Yamaguchi University School
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