Cholagogic Action of the Essential Oil Obtained from Curcuma xanthorrhiza ROXB.
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概要
- 論文の詳細を見る
The cholagogic effects of the essential oils obtained by steam distillation from the rhizome of Curcuma longa L. (C. longa) and Curcuma xanthorrhiza ROXB. (C. xanthorrhiza), which have traditionally been used as cholagoues in Indonesia, were studied using anesthetized rats. Oral administration of the essential oils caused a persistent increase of bile secretion, the essential oil of C. xanthorrhiza being slightly more active than that of C. longa. The active principle of the essential oil of C. xanthorrhiza isolated by silica gel column chromatography was shown to contain d-camphor by GC-Mass and TLC. The essential oil and d-camphor both caused a long lasting increase of bile secretion involving increases both in the amount of total bile acids and in the solid matter weight in the excreted bile. These results suggest that the cholagogic effect of the essential oil is attributable to d-camphor contained in it and that the increase in bile secretion induced either by the essential oil or d-camphor is partly due to the increase in the total bile acids in the excretive bile.
- 日本生薬学会の論文
- 1988-12-20
著者
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Ozaki Yukihiro
Division Of Pharmacognosy And Phytochemistry National Institute Of Health Sciences
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Ozaki Yukihiro
Division Of Pharmacognosy And Phytochemistry National Institute Of Hygienic Sciences
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Liang Oei
Department Of Chemistry Institute Of Technology Bandung
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Ozaki Yukihiro
Division of Pharmacognosy and Phytochemistry , National Institute of Health Sciences
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