J0204-1-5 電気インピーダンス法による軟骨組織の水分状態の評価([J0204-1]バイオトライボロジー(1))

概要

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The purpose of this study was to investigate the correlation between electric impedance and water status of articular cartilage. Cartilage specimens harvested from porcine knee joints were treated by collagenase solution to digest collagen fibrils and by hyaluronidase solution to digest proteoglycan. According to electric impedance measurement and compressive test, the electric impedance and the compressive stiffness for both groups decreased with treatment time, and the electric impedance showed a significant positive relation with the compressive stiffness. Water content for the collagenase group increased with treatment time, whereas that for the hyaluronidase group did not change with treatment time. The electric impedance and the compressive stiffness for the hyaluronidase group decreased with increasing permeability due to digestion of proteoglycan, and those for the collagenase group decreased with increasing water content and permeability. It is suggested that the electric impedance is not only water content but also permeability of articular cartilage.
一般社団法人日本機械学会の論文
2010-09-04